Encapsulation News & Publications2022-09-01T14:09:34+00:00

Key Achievements

  • Development of new to the world microencapsulated probiotics, stable in UHT beverage production
  • Commissioning of bespoke commercial production line for probiotic micro encapsulation
  • Development of immunity enhancing encapsulated vitamins and probiotics in response to Covid 19
  • Commencement of commercial supply of micro encapsulated functional ingredients
  • Opening of Microencapsulation Centre of Excellence in Carrigtwohill Co Cork
  • Granting of 13 patents for innovative micro encapsulation technology

Awards & Nominations

Publications & Links


Doherty, S.B., Gee, V.L., Ross, R.P., Stanton, C., Fitzgerald, G.F., and Brodkorb, A. (2010) Efficacy of whey protein gel networks as potential viability-enhancing scaffolds for cell immobilization of Lactobacillus rhamnosus GG. Journal of Microbiological Methods. 80, 231-241.

Doherty, S.B., Wang, L., Ross, R.P., Stanton, C., Fitzgerald, G.F., Brodkorb, A., (2010a) Use of viability staining in combination with Flow Cytometry for rapid viability assessment of Lactobacillus rhamnosus GG in complex protein matrices. Journal of Microbiological Methods. 82, 301-310.

Doherty, Auty, M.A., Ross, R.P., Stanton, C., Fitzgerald, G.F., Brodkorb, A., (2011a) Development and characterisation of whey protein micro-beads as potential matrices for probiotic protection. Food Hydrocolloids 25, 1604-1617.

Doherty, S.B., Auty, M.A., Stanton, C., Ross, R.P., Fitzgerald, G.F., Brodkorb, (2011b) Survival of entrapped Lactobacillus rhamnosus GG in whey protein micro-beads during simulated ex vivo gastro-intestinal transit. International Dairy Journal, In Press (September 2011).

Doherty, S.B., Upadrasta, A., Lawlor, P.G., Ross, R.P., Stanton, C., Fitzgerald, G.F., Brodkorb, A., (2011c) Evaluation of whey protein micro-bead transit time in the porcine gastro-intestinal tract, Journal of Microencapsulation, Published, October 2011.

Doherty, S.B., Auty, M.A., Ross, R.P., Stanton, C., Fitzgerald, G.F., Brodkorb, A., (2011d) Application of whey protein micro-bead coatings for enhanced strength and probiotic protection during fruit juice storage and gastric incubation, Journal of Micriencapsulation, Published, October, 2011.

Doherty, S.B., Upadrasta, A., Auty, M.A.E., Lawlor, P.G., Walsh, M.C., Ross, R.P., Stanton, C., Fitzgerald, G.F. and Brodkorb, A. (2011e) Application of whey protein micro-beads for improved probiotic delivery and functionality during in vivo gastro- intestinal transit, Published, November 2014

Heade J., Bleiel S.B., Brayden D.J. (2016) “Overcoming the obstacles associated with oral delivery of peptides” Engineers Journal.

Pre/probiotic encapsulation technology for novel infant and toddler formulations. (Presentation) Probiota 2014, Amsterdam, The Netherlands, 4-5th February 2014.

Kent R.M., Stack H.M., O’Connor P.M., Fitzgerald G.F., Hill C., Stanton C., Ross R.P. Enzymatic production of casein-derived bioactive peptides; In silico prediction to pilot scale. Submission in progress

Guinane C.M., Kent R.M., O’Connor P.M., Fitzgerald G.F., Hill C., Stanton C., Ross R.P. Recombinant Lactobacillus paracasei strain producing active gut hormone Glucagon-like peptide-1 (GLP-1). Submission in progress

Heade J., Maher S., Bleiel S.B., Brayden D.J., (2018) “Labrasol® and salts of medium chain fatty acids can be combined in low concentrations to increase the permeability of a macromolecule marker across isolated rat intestinal mucosae” J. Pharm. Sci. (under review)

Guinane C.M., Kent R.M., Norberg S., Hill C., Fitzgerald G.F., Stanton C., Ross R.P. (2010) Host specific diversity in Lactobacillus johnsonii as evidenced by a major chromosomal inversion and phage resistance mechanisms. PLoS One. 2011 Apr 20;6(4):e18740.

Guinane C.M., Kent R.M., Hill C., Fitzgerald G.F., Stanton C., Ross R.P. (2010) Genomic rearrangements in the intestinal bacterium Lactobacillus johnsonii. (Poster presentation) US/Ireland Functional Foods Conference 2010, Cork, Ireland.

RM Kent, SB Doherty (2014) Probiotic bacteria in infant formula and follow-up formula: Microencapsulation using milk and pea proteins to improve microbiological quality- Food research international, Elsevier.

Alleleyn, A.M.E.; Van Avesaat, M.; Ripken, D.; Bleiel, S.B.; Keszthelyi, D.; Wilms, E.; Troost, F.J.; Hendriks, H.F.J.; Masclee, A.A.M. (2018) The Effect of an Encapsulated Nutrient Mixture on Food Intake and Satiety: A Double-Blind Randomized Cross-Over Proof of Concept Study. Nutrients10, 1787. DOI: https://doi.org/10.3390/nu10111787

Hone, M., Kent, R.M., Scotto di Palumbo, A., Bleiel, S.B., De Vito, V., & Egan, B., (2017). Plasma Creatine Kinetics After Ingestion of Microencapsulated Creatine Monohydrate with Enhanced Stability in Aqueous Solutions, Journal of Dietary Supplements, 14:4, 433-445, DOI: 10.1080/19390211.2016.1267060

Kent, R.M.; Fitzgerald, G.F.; Hill, C.; Stanton, C.; Ross, R.P. (2015) Novel Approaches to Improve the Intrinsic Microbiological Safety of Powdered Infant Milk Formula. Nutrients, 7, 1217-1244.

Prieto ML, O’Sullivan L, Tan SP, McLoughlin P, Hughes H, O’Donovan O, et al. (2014) Evaluation of the Efficacy and Safety of a Marine-Derived Bacillus Strain for Use as an In-Feed Probiotic for Newly Weaned Pigs. PLoS ONE 9(2): e88599. https://doi.org/10.1371/journal.pone.0088599

Ryan, P.M., Patterson, E., Kent, R.M. et al. (2017) Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents. Sci Rep 7, 13523. https://doi.org/10.1038/s41598-017-14010-x

Aisling M Mangan, Werd Al Najim, Niamh McNamara, William P Martin, Andrius Antanaitis, Sinéad B Bleiel, Robert M Kent, Carel W le Roux, Neil G Docherty, (2019) Effect of Macronutrient Type and Gastrointestinal Release Site on PYY Response in Normal Healthy Subjects, The Journal of Clinical Endocrinology & Metabolism, Volume 104, Issue 9, Pages 3661–3669, https://doi.org/10.1210/jc.2018-01697

Bleiel S.B., Kent R.M., Brodkorb A. (2017) Encapsulation Efficiency and Capacity of Bioactive Delivery Systems. In: Roos Y., Livney Y. (eds) Engineering Foods for Bioactives Stability and Delivery. Food Engineering Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-6595-3_6

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